Mother’s genes can impact ageing process
As we age, our cells change and become damaged. Now, researchers at Karolinska Institutet and the Max Planck Institute for Biology of Aging have shown that ageing is determined not only by the accumulation of changes during our lifetime but also by the genes we acquire from our mothers. The results of the study are published in the journal Nature. There are many causes of aging that are determined by an accumulation of various kinds of changes that impair the function of bodily organs. Of particular importance in aging, however, seems to be the changes that occur in the cell’s power plant — the mitochondrion. This structure is located in the cell and generates most of the cell’s supply of ATP which is used as a source of chemical energy. “The mitochondria contains their own DNA, which changes more than the DNA in the nucleus, and this has a significant impact on the aging process,” said Nils-Göran Larsson, Ph.D., professor at the Karolinska Institutet and princ...